Core Competencies and Technical Knowledge
Our Core Competencies
Controlled Venom Sourcing: In line with WHO TRS guidance discouraging wild-caught collection and due to the lack of traceability and difficulties in ensuring effective quality control of venoms, Padra Serum operates a secured and on-site serpentarium that houses Category-1 and Category-2 Iranian venomous species.
High-purity Fractionation: As mentioned in WHO’s TRS 1004, caprylic acid–based process delivers superior product purity, reduced protein aggregation, and higher recovery versus ammonium sulfate precipitation from approximately between 30% and 40% to between 60% and 75%.
Enhanced Process Yield: Optimized protocols ensure significantly higher antibody recovery and batch-to-batch consistency.
Advanced Viral Safety: Dual inactivation (low-pH digestion and caprylic acid treatment) complemented with nanofiltration as an additional viral removal step ensures robust viral clearance, in accordance with WHO guideline.
Ultrafiltration System: Ultrafiltration eliminates low-molecular-mass contaminants.
Global Validation and Recognition: Through participation in the WHO’s 2021 Risk-Benefit Assessment Call, independent QC testing at the Instituto de Biomedicina de Valencia (WHO-designated reference laboratory located in Spain) confirmed strong venom toxin binding across homologous species.
Our Assets
Our Assets
Serpentarium:
Padra Serum operates a serpentarium as a separate building on the farm, which is fully secured, environmentally controlled and designed for the breeding and farming of all medically important venomous snake species native to Iran.
Equine Farm:
Padra Serum’s farm has stables for housing horses and blood collecting stations are provided by a capacity of 7 horses in each blood collecting cycle with full traceability and animal-welfare oversight.
Plasma Refinery Facility:
Padra Serum Alborz operates a plasma fractionation facility with an annual processing capacity of 10,000 liters of hyperimmune plasma. Purification processes utilize validated low-pH treatment, caprylic acid precipitation, and nanofiltration by ensuring quality, safety, and efficacy in accordance with WHO and IFDA regulations.
Quality Control Laboratories:
Padra Serum is equipped with two laboratories focused on the following functions:
Veterinary laboratory for continuous monitoring of serological and biochemical horses’ health parameters.
Pharmaceutical QC laboratory for in-process and final product quality control.
